Facts we can source about this employer, with the year of every figure.
By AtiveSite · Published 07/11/2026 · Updated 08/11/2026 · Every figure is linked to its source below.
Centene ranks #128 among the 200 largest US-headquartered employers, with about 61,100 employees worldwide (2025). It is headquartered in Clayton, Missouri.
| Fact ⇅ | Value ⇅ |
|---|---|
| Rank among the 200 | 128 |
| Headquarters | Clayton, Missouri |
| Industry | Managed healthcare, Health insurance, Pharmacy |
| Employees (global) | 61,100 (2025) |
| Founded | 1984 |
Headcount is global, includes workers outside the US and may differ from the company's latest annual report.
Centene ranks 128 of the 200 largest US-headquartered employers in our list, with about 61,100 employees worldwide (2025). That is roughly the number of people who live in Vineland, New Jersey. It was founded 1984.
The company's headquarters state, Missouri, has 6,191,814 residents, a median household income of $70,702 and an unemployment rate of 3.6%. The occupations with the most jobs in the state are General and Operations Managers (median $79,300); Home Health and Personal Care Aides (median $33,080); Registered Nurses (median $81,780); Cashiers (median $30,520); Stockers and Order Fillers (median $36,710). A large employer headquartered there hires from the same pool, plus specialised roles tied to its industry (Managed healthcare, Health insurance, Pharmacy).
Honest limits. The headcount is the company's global figure as reported in its public filings and compiled on Wikipedia. It does not say how many people work at the headquarters, and it does not mean the company is hiring. For open positions, use the company's own careers page, linked in the official links below.
These links go to official sources and open in a new window. The first one is the government's or company's own site as listed in Wikidata (property "official website"); check it before relying on it.
The company's home state is Missouri: median household income $70,702, unemployment 3.6%, state income tax: graduated, top rate 4.70%.
City guide: Clayton (median rent $1,692, median household income $123,000).
| Company ⇅ | Industry ⇅ | Employees ⇅ |
|---|---|---|
| Panera Bread | 140,000 | |
| O'Reilly Automotive | Retail | 93,269 |
| Emerson Electric Co. | Automation, Electrical equipment | 71,000 |
| Company ⇅ | Headquarters ⇅ | Employees ⇅ |
|---|---|---|
| UnitedHealth Group | Minnesota | 390,000 |
| HCA Healthcare | Tennessee | 316,000 |
| CVS Health | Rhode Island | 300,000 |
| CommonSpirit Health | Illinois | 175,000 |
| Thermo Fisher Scientific | Massachusetts | 125,000 |
| Elevance Health | Indiana | 104,200 |
| Adventist Health System/Sunbelt | Florida | 100,000 |
| Tenet Healthcare | Texas | 98,000 |
| DaVita | Colorado | 78,000 |
| Intermountain Health | Utah | 68,000 |
| Cigna Group | Connecticut | 67,700 |
| Humana | Kentucky | 67,060 |
About 61,100 worldwide (2025), per the company's reported figure.
Clayton, Missouri.
It ranks #128 among the 200 largest US-headquartered employers by global headcount.